The SFB/TR-103 is a collaborative research center funded by the Deutsche Forschungsgemeinschaft, (DFG). The focus of SFB/TR-103 is on Ni- and Co-base single crystal superalloys (SXs) with gamma / gamma prime microstructures. SXs are used to make blades, which operate in gas turbines that are used in power plants and aero engines. They must have a good creep, high temperature fatigue and corrosion resistance, because they have to withstand mechanical loads at high temperatures in aggressive atmospheres. For progress, scientists from different areas including materials science (alloy development, microscopy), materials technology (casting, hot isostatic pressing, additive manufacturing, coating), mechanical engineering (testing, mechanical modelling), physics and chemistry (fundamental thermodynamics and kinetics) must join forces. The need for interdisciplinary research in this fascinating engineering materials field is highlighted and some examples for novel types of collaborations which bridge gaps between different scientific fields are given. Then the need for scale bridging materials science is highlighted. It applies to the microstructural characterization field, where atomistic input (nm-scale: atom spacings, segregation to interfaces) is as important as input from the micro (µm-scale: dislocations; precipitate morphology) and macro scales (mm-scale: dendrite spacings, dimensions of bulk specimens and components). Scale bridging is also a challenge for mechanical testing, where the mechanical properties of individual phases (gamma and gamma prime) and from different microstructural regions (prior interdendritic and dendritic regions) are as important as the mechanical behavior of the bulk material. Insight can be gained through new test techniques like in-situ SEM micro shear testing or circular notched miniature specimen creep testing. Efforts to bridge scales drives research in the modelling field, where atomistic, mesoscopic and macroscopic approaches can benefit from each other. In its second four year funding period (running since 2016) SFB/TR 103 has developed into a fascinating research environment, where researchers from the Ruhr-Universität Bochum (RUB) and the Friedrich-Alexander-Universität Erlangen Nürnberg (FAU) join forces with external partners from MPIE Düsseldorf, DLR Köln and FZ Jülich to establish the scientific basis for the development of the next generation of SXs (see: www.sfb-tr103.de).