This symposium focuses on fundamental aspects of the thermodynamics of materials and the kinetics of microstructure evolution associated with non-equilibrium states, phase transformations and defects. Experimental and computational approaches comprise, but are not limited to: CALPHAD-type modeling, First-principle and Monte-Carlo methods, Phase Field approaches, experimental phase diagram investigations (materials constitution), experimental thermodynamics and kinetics. Materials of interest are metals and ceramics, respectively. However, applications referring to composites, soft matter and biological materials are welcome to explore synergetic approaches. Also theory and applications of thermodynamics and kinetics for “materials behavior in engineering systems”, e.g. for energy storage and conversion, are welcome.