Initial study on 3D printing of piezoelectric barium titanate ceramics for bone tissue engineeringWednesday (26.09.2018) 15:00 - 15:15 S1/01 - A01 Part of:
This study presents a customized 3D printing process to fabricate piezoelectric, biocompatible ceramics for bone tissue engineering. Piezoelectric ceramics are widely used in today's industry and in various applications known from daily life. The transfer of these ceramics into medical applications, such as electrically active implants with the potential of enhanced tissue regeneration, seems to be highly desirable. Here we report the successful 3D printing of barium titanate (BaTiO3), a lead-free, biocompatible, ferro- and piezoelectric ceramic. For the printing process, a powder-based approach was applied, using a composite material mixture of BaTiO3, polyethylmethacrylat and hydroxyapatite. Via binder jetting 3D printing, the selective bonding of the particulate material was achieved. Cylindrical interconnected porous scaffolds with an average pore diameter of 1 mm were fabricated. Subsequent, the scaffolds were thermally debinded to remove the remaining organic residuals. The debinding was followed by a sintering process to increase the density and the mechanical integrity of the scaffolds. Afterwards, the scaffolds were characterised in terms of size accuracy, porosity and mechanical integrity by compression testing. The results represent the first milestone for the fabrication of piezoelectric barium titanate scaffolds via 3D printing. In further studies, the focus will be on the activation and furthermore the customization of the piezoelectric properties for the application as an electrically active implant.