A comparative study of additively manufactured and as-cast Al12Co22Cr22Fe22Ni22 high entropy alloy (HEA) has been performed. The laser metal deposition (LMD) technique with laser power and laser beam diameter of 970 W and 1.8 mm respectively, was employed to deposit HEA powder on the 1.2365 steel substrate under argon atmosphere. For the present study, a bidirectional scanning strategy with scanning velocity of 800 mm/min has been used. As a reference, the cylindrical samples with equivalent composition were centrifugally casted in a copper mold under argon atmosphere. The microstructure was investigated with special emphasis on phase distribution and texture, also including inter layer boundaries for the LMD specimens. Tensile tests were performed on miniature samples at RT, 400 and 700 oC for as-cast reference as well as for LMD samples in building and transverse directions. Plastic deformation and strain localization were investigated during in-situ tensile tests with EBSD mapping. On this basis, a thorough comparison between LMD and as-cast materials will be presented.